Impact of a chromosome X STR Decaplex in deficiency paternity cases
نویسندگان
چکیده
Deficiency paternity cases, characterized by the absence of the alleged father, are a challenge for forensic genetics. Here we present four cases with a female child and a deceased alleged father in which the analysis of a set of 21 or 22 autosomal STRs (AS STRs) produced results within a range of doubt when genotyping relatives of the alleged father. Aiming to increase the Paternity Index (PI) and obtain more reliable results, a set of 10 X-linked STR markers, developed by the Spanish and Portuguese Group of the International Society for Forensic Genetics (ISFG), was then added. Statistical analysis substantially shifted the results towards the alleged fatherhood in all four cases, with more dramatic changes when the supposed half-sister and respective mother were the relatives tested.
منابع مشابه
Forensic Science International: Genetics
X chromosome short-tandem repeats (X-STR) assays are helpful in complex kinship testing cases where autosomal and Y chromosome analyses convey little information. Their application has distinct advantages in mother-son and father-daughter kinship testing. Paternal relatives can be tested even in cases of deficiency paternity [1]. The purpose of this study was to create an allele frequency datab...
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عنوان ژورنال:
دوره 36 شماره
صفحات -
تاریخ انتشار 2013